Andersen J T, Bradley W E
Br J Urol. 1976 Oct;48(5):341-5. doi: 10.1111/j.1464-410x.1976.tb06649.x.
A new technique for recording of the urethral closure pressure profile using gas-inflation and simultaneous EMG-recording from the urethra is described. With the present technique, the parameters of the urethral closure pressure profile in healthy volunteers were in accordance with previous reports using water-infusion. The effect of alpha-adrenergic blockade on the pressure profile was studied in a series of patients. Half of the patients showed a marked reduction of the intraurethral pressure in the presphincteric part of the profile after alpha-adrenergic blockade. This indicated that sympathetic innervated smooth musculature gives a significant contribution to the total intraurethral pressure.
本文描述了一种使用气体充盈并同步记录尿道肌电图来记录尿道闭合压力曲线的新技术。采用该技术，健康志愿者的尿道闭合压力曲线参数与先前使用水灌注法的报道一致。我们在一系列患者中研究了α-肾上腺素能阻滞剂对压力曲线的影响。一半的患者在接受α-肾上腺素能阻滞剂治疗后，其压力曲线括约肌前部的尿道内压显著降低。这表明交感神经支配的平滑肌组织对尿道内总压力有显著贡献。
