Chastikova A V, Starostina Z D, Strugatskaia G S
Antibiotiki. 1978 Aug;23(8):747-51.
Penicillin sensitivity of gonococci isolated from patients with relapses and reinfection of gonorrhea was studied. The results of the study were compared with those of the sensitivity tests in primary patients. The gonococcal strains with decreased sensitivity to penicillin were isolated from 82 per cent of the gonorrhea relapses, 47.8 per cent of the patients with reinfection and 33.2 per cent of the primary patients. The average sensitivity of the gonococcal strains isolated from the patients with relapses was 0.404 U/ml, while that in the primary patients and the patients with reinfection was 0.136 U/ml. Strains sensitive to 0.6--1.2 U/ml predominated among gonococci with decreased sensitivity in the patients with relapses, while in the primary patients and the ones with reinfection the value amounted to 0.1--0.2 U/ml. The penicillin sensitivity of gonococci may be used as a parameter in differential diagnosis of relapses and reinfection of gonorrhea.
对从淋病复发和再感染患者中分离出的淋球菌的青霉素敏感性进行了研究。将研究结果与初发患者的敏感性试验结果进行了比较。对青霉素敏感性降低的淋球菌菌株在82%的淋病复发患者、47.8%的再感染患者和33.2%的初发患者中被分离出来。从复发患者中分离出的淋球菌菌株的平均敏感性为0.404 U/ml，而在初发患者和再感染患者中为0.136 U/ml。在复发患者中，对0.6--1.2 U/ml敏感的菌株在敏感性降低的淋球菌中占主导地位，而在初发患者和再感染患者中该值为0.1--0.2 U/ml。淋球菌的青霉素敏感性可作为淋病复发和再感染鉴别诊断的一个参数。
