Serruys P W, Hagemeijer F, Bom A H, Roelandt J
Arch Mal Coeur Vaiss. 1978 Jun;71(6):611-26.
The anatomical and functional abnormalities which are the basis of septal defects and valvular incompetence can be visualised directly by two-dimensional contrast echocardiology. Although right-left shunts at atrial or ventricular level can easily be discovered and visualised after injection peripherally, the same is not true of left-right ventricular shunts; these are not detectable. As for left-right shunts (as demonstrated by oxymetry) at the atrial level, these are in a separate category; the passage of ultrasonic contrast medium from right to left is inconstant. This technique also allows the study of abnormal blood flow: tricuspid incompetence, turbulence caused by prosthetic valves, etc.
作为房间隔缺损和瓣膜关闭不全基础的解剖及功能异常可通过二维对比超声心动图直接显示。虽然经外周注射后,心房或心室水平的右向左分流很容易被发现和显示,但左右心室分流情况并非如此;这些无法检测到。至于房间隔水平的左向右分流(通过血氧测定证实),它们属于另一类情况;超声造影剂从右向左的通过并不恒定。这项技术还可用于研究异常血流:三尖瓣关闭不全、人工瓣膜引起的湍流等。