Miller P, Church M K
Clin Exp Immunol. 1976 Jul;25(1):177-9.
The anaphylactic reaction in the pinna of a mouse actively sensitized to horse serum is mediated by IgG1 and IgE antibodies. Anaphylactic sensitivity is subject to diurnal variation, peak sensitivity occurring at 16.00 hours and minimum sensitivity at 10.00 hours. Anaphylactic sensitivity also varied with the season of the year, being lower during June and July than in the rest of the year, when the reaction was fairly constant.
对马血清主动致敏的小鼠耳廓中的过敏反应由IgG1和IgE抗体介导。过敏敏感性存在昼夜变化,在16:00时敏感性最高,在10:00时敏感性最低。过敏敏感性也随一年中的季节而变化,6月和7月的敏感性低于一年中的其他时间,其他时间反应相当稳定。