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脊柱手术中自体输血的审计。

Audit of autotransfusion in spine surgery.

作者信息

Shulman G, Solanki D R, Nicodemus C L, Flores I M, Hadjipavlou A G

机构信息

Department of Pathology, University of Texas Medical Branch, Galveston 77555-0192, USA.

出版信息

Int Orthop. 1998;22(5):303-7. doi: 10.1007/s002640050265.

Abstract

A prospective evaluation has been undertaken of 382 patients undergoing reconstructive spine surgery during a thirty-six month period. Acute normovolaemic haemodilution and haemapheresis for blood component sequestration was used in 80 patients in the operating theatre. An average of two units each of freshly collected autologous red cells and fresh plasma together with a therapeutic dose of a plateletpheresis product were prepared for each patient prior to surgical incision. The same supplies and equipment were subsequently used for conventional blood salvage and autotransfusion. The other 302 patients received salvaged blood only. Of the total blood transfused, autologous red cells comprised 87% of sequestration and 49% of autotransfusion-only patients. Each group received the same total perioperative red blood cell support. The cost for one red cell equivalent by intraoperative autologous transfusion was competitive with that of providing one unit of cross-matched allogeneic red cells. As compared with salvage alone, sequestration combined with salvage was even more cost effective and decreased reliance on allogenic products and preoperative autologous blood donations. The rate of transfusing autologous blood products was markedly increased.

摘要

对382例在36个月期间接受脊柱重建手术的患者进行了前瞻性评估。80例患者在手术室采用急性等容血液稀释和血液成分分离的血液单采术。在手术切口前,为每位患者平均制备了两单位新鲜采集的自体红细胞和新鲜血浆以及治疗剂量的血小板单采产品。随后,相同的耗材和设备用于常规血液回收和自体输血。另外302例患者仅接受回收血液。在输注的全血中,自体红细胞在血液成分分离组中占87%,在仅接受自体输血的患者中占49%。每组接受相同的围手术期红细胞总量支持。术中自体输血产生一个红细胞当量的成本与提供一单位交叉配型的异体红细胞的成本具有竞争力。与单纯回收相比,血液成分分离联合回收更具成本效益,减少了对异体产品和术前自体献血的依赖。自体血液制品的输注率显著提高。

相似文献

1
Audit of autotransfusion in spine surgery.脊柱手术中自体输血的审计。
Int Orthop. 1998;22(5):303-7. doi: 10.1007/s002640050265.
2
Augmented autologous transfusions in major reconstructive spine surgery.脊柱重建大手术中的强化自体输血
J Clin Apher. 1998;13(2):62-8. doi: 10.1002/(sici)1098-1101(1998)13:2<62::aid-jca3>3.0.co;2-6.
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