Oyelese K O, Schwärzler P, Coates S, Sanusi F A, Hamid R, Campbell S
Department of Obstetrics and Gynaecology, St. George's Hospital, London, UK.
Ultrasound Obstet Gynecol. 1998 Dec;12(6):434-8. doi: 10.1046/j.1469-0705.1998.12060434.x.
Vasa previa is a cause of sudden unanticipated fetal death, with a fetal mortality of 33-100%. Transvaginal sonography (TVS) and color Doppler may aid in making the diagnosis antenatally, allowing elective Cesarean delivery, thereby avoiding fetal death from exsanguination which would occur if the membranes were allowed to rupture in labor. Whilst it is not feasible to screen all pregnant women for vasa previa, antenatal examination with TVS and color Doppler of women at risk, specifically those with low-lying placentas, bi-lobed, multi-lobed and succenturiate-lobed placentas, multiple pregnancies and pregnancies resulting from in vitro fertilization may lead to antenatal diagnosis of the condition. We present the last three cases of vasa previa to have occurred in our institution, two of which were diagnosed antenatally using TVS and color Doppler. In all three cases, routine 20-week obstetric sonography revealed low-lying placentas; in only one of these did the placenta remain low at term. A low-lying placenta at 20 weeks may be a risk factor for vasa previa; we suggest that further studies be carried out to ascertain this. Judicious use of TVS and color Doppler in women considered at risk of vasa previa may help to reduce the mortality from this condition.
前置血管是导致胎儿意外猝死的原因之一,胎儿死亡率为33%-100%。经阴道超声检查(TVS)和彩色多普勒检查有助于产前诊断,从而可以选择剖宫产分娩,避免因胎膜在分娩时破裂导致胎儿失血而死亡。虽然对所有孕妇进行前置血管筛查不可行,但对高危女性,特别是那些胎盘低置、双叶、多叶和副叶胎盘、多胎妊娠以及体外受精妊娠的女性,采用TVS和彩色多普勒进行产前检查可能会实现该病的产前诊断。我们报告了本院最近发生的三例前置血管病例,其中两例通过TVS和彩色多普勒进行了产前诊断。在所有三例中,常规20周产科超声检查均显示胎盘低置;其中只有一例胎盘在足月时仍为低置状态。20周时胎盘低置可能是前置血管的一个危险因素;我们建议开展进一步研究以确定这一点。对有前置血管风险的女性合理使用TVS和彩色多普勒可能有助于降低该病的死亡率。