5-溴脱氧尿苷对鸡胚血岛细胞红细胞生成的抑制和刺激作用
Inhibition and stimulation by 5-bromodeoxyuridine of erythropoiesis by chick blood island cells.
作者信息
Wainwright S D, Wainwright L K
出版信息
Experientia. 1976 Nov 15;32(11):1473-4. doi: 10.1007/BF01937442.
PMID:992003
Abstract
Erythropoiesis in liquid cultures of cell populations resolved from chick blastodiscs at the primitive streak and head-fold stages was totally inhibited by 5-8 mug/ml of 5-bromodeoxyuridine. However, concentrations of 0.2 mug/ml of the nucleoside enhanced the number of erythroid cells formed.
摘要
从处于原条期和头褶期的鸡胚盘分离出的细胞群体进行液体培养时，5-8微克/毫升的5-溴脱氧尿苷会完全抑制红细胞生成。然而，0.2微克/毫升的该核苷浓度会增加形成的红细胞数量。
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