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5-溴脱氧尿苷对鸡胚血岛细胞红细胞生成的抑制和刺激作用

Inhibition and stimulation by 5-bromodeoxyuridine of erythropoiesis by chick blood island cells.

作者信息

Wainwright S D, Wainwright L K

出版信息

Experientia. 1976 Nov 15;32(11):1473-4. doi: 10.1007/BF01937442.

DOI:10.1007/BF01937442
PMID:992003
Abstract

Erythropoiesis in liquid cultures of cell populations resolved from chick blastodiscs at the primitive streak and head-fold stages was totally inhibited by 5-8 mug/ml of 5-bromodeoxyuridine. However, concentrations of 0.2 mug/ml of the nucleoside enhanced the number of erythroid cells formed.

摘要

从处于原条期和头褶期的鸡胚盘分离出的细胞群体进行液体培养时，5-8微克/毫升的5-溴脱氧尿苷会完全抑制红细胞生成。然而，0.2微克/毫升的该核苷浓度会增加形成的红细胞数量。

相似文献

1
Inhibition and stimulation by 5-bromodeoxyuridine of erythropoiesis by chick blood island cells.5-溴脱氧尿苷对鸡胚血岛细胞红细胞生成的抑制和刺激作用
Experientia. 1976 Nov 15;32(11):1473-4. doi: 10.1007/BF01937442.
2
Stimulation by isoproterenol of erythropoiesis in cultures of dispersed cells of the primitive-streak chick blastodisc.
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The effects of 5-bromodeoxyuridine on yolk sac erythropoiesis in the chick embryo.5-溴脱氧尿苷对鸡胚卵黄囊红细胞生成的影响。
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Preparation of cell populations with stabilized erythropoietic potential from the primitive streak chick blastodisc: some implications for control of gastrulation.从原条期鸡胚盘制备具有稳定造血潜能的细胞群体：对原肠胚形成控制的一些启示。
Can J Biochem. 1978 Jun;56(6):430-9. doi: 10.1139/o78-067.
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Differentiation in the presence of bromodeoxyuridine id "all-or-none".
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Erythropoietic cell cultures from chick embryos.来自鸡胚的红细胞生成细胞培养物。
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本文引用的文献

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A series of normal stages in the development of the chick embryo.鸡胚胎发育的一系列正常阶段。
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REGULATION OF THE INITIATION OF CHICK EMBRYO HEMOGLOBIN SYNTHESIS.鸡胚血红蛋白合成起始的调控
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5-BROMODEOXYURIDINE: EFFECT ON MYOGENESIS IN VITRO.5-溴脱氧尿苷：对体外肌生成的影响。
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Evidence of a microsomal factor required for in vitro development of pseudo-triptophan synthase activity by extracts of Neurospora crassa.粗糙脉孢菌提取物在体外产生假色氨酸合酶活性所需微粒体因子的证据。
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A clonal study of the reversible inhibition of muscle differentiation by the halogenated thymidine analog 5-bromodeoxyuridine.卤代胸腺嘧啶类似物5-溴脱氧尿苷对肌肉分化可逆抑制的克隆研究。
Dev Biol. 1969 Jun;19(6):527-48. doi: 10.1016/0012-1606(69)90036-0.
6
The effects of 5-Bromodeoxyuridine on the differentiation of chondrocytes in vitro.5-溴脱氧尿苷对体外软骨细胞分化的影响。
Dev Biol. 1969 May;19(5):415-35. doi: 10.1016/0012-1606(69)90080-3.
7
Inhibition of mammary gland differentiation in vitro by 5-bromo-2'-deoxyuridine.5-溴-2'-脱氧尿苷对体外乳腺分化的抑制作用。
J Biol Chem. 1971 Mar 25;246(6):1814-9.
8
5-bromodeoxyuridine-induced differentiation of a neuroblastoma.5-溴脱氧尿苷诱导神经母细胞瘤分化
Proc Natl Acad Sci U S A. 1970 Sep;67(1):247-54. doi: 10.1073/pnas.67.1.247.
9
The effects of 5-bromodeoxyuridine on yolk sac erythropoiesis in the chick embryo.5-溴脱氧尿苷对鸡胚卵黄囊红细胞生成的影响。
J Cell Biol. 1971 Mar;48(3):523-32. doi: 10.1083/jcb.48.3.523.
10
Erythropoietic cell cultures from chick embryos.来自鸡胚的红细胞生成细胞培养物。
J Cell Biol. 1972 Jul;54(1):98-106. doi: 10.1083/jcb.54.1.98.