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用对流免疫电泳法检测阿米巴肝脓肿中的循环抗原

Detection of circulating antigen in amoebic liver abscess by counter-current immunoelectrophoresis.

作者信息

Parija S C, Karki B M S

出版信息

J Med Microbiol. 1999 Jan;48(1):99-101. doi: 10.1099/00222615-48-1-99.

DOI:10.1099/00222615-48-1-99
PMID:9920132
Abstract

Fifty serum samples from patients with amoebic liver abscess and 50 from subjects who had not suffered from the disease (25 from patients with other, chiefly parasitic, infections and 25 from healthy blood donors, staff or students) were tested for circulating amoebic antigen by counter-current immuno-electrophoresis (CIEP). Amoebic antigen was detected in 38 sera (76%) from cases of amoebic liver abscess, but in none of the other sera. Although CIEP is only moderately sensitive, the high specificity suggests that this simple test may be useful in the diagnosis of amoebic liver abscess.

摘要

采用对流免疫电泳(CIEP)对50份阿米巴肝脓肿患者的血清样本以及50份未患该病的受试者血清样本(其中25份来自患有其他主要为寄生虫感染的患者,25份来自健康献血者、工作人员或学生)进行循环阿米巴抗原检测。在阿米巴肝脓肿患者的38份血清(76%)中检测到了阿米巴抗原,而在其他血清样本中均未检测到。尽管CIEP的敏感性仅为中等,但高特异性表明这项简单检测可能对阿米巴肝脓肿的诊断有用。

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