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美国黑色素瘤发病率及死亡率的最新情况。

Update on the incidence and mortality from melanoma in the United States.

作者信息

Hall H I, Miller D R, Rogers J D, Bewerse B

机构信息

Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.

出版信息

J Am Acad Dermatol. 1999 Jan;40(1):35-42. doi: 10.1016/s0190-9622(99)70562-1.

DOI:10.1016/s0190-9622(99)70562-1
PMID:9922010
Abstract

BACKGROUND

Increases in the incidence of malignant melanoma have been among the largest of all cancers in the United States.

OBJECTIVE

We report updated trends in melanoma rates among the US white population.

METHODS

Incidence and mortality rates were calculated for 1973 to 1994. Trends were examined with stratification by state, age, and sex, and by anatomic site, stage, and melanoma thickness at diagnosis.

RESULTS

Melanoma incidence and mortality rates increased dramatically from 1973 to 1994, rising 120.5% and 38.9%, respectively. In recent years, however, rates for most age-sex groups appeared to stabilize or even decline. Male patients continued to have higher incidence and mortality rates than female patients, but for both male and female patients the largest increases by site were for the trunk. A large proportion of melanomas were detected in the local stage and with a thickness less than 0.75 mm.

CONCLUSION

Prevention of sun exposure is recommended to reverse the high incidence rates of melanoma.

摘要

背景

在美国,恶性黑色素瘤发病率的增长幅度在所有癌症中位居前列。

目的

我们报告美国白人人群中黑色素瘤发病率的最新趋势。

方法

计算1973年至1994年的发病率和死亡率。通过按州、年龄、性别以及诊断时的解剖部位、分期和黑色素瘤厚度进行分层来研究趋势。

结果

1973年至1994年,黑色素瘤发病率和死亡率急剧上升,分别上升了120.5%和38.9%。然而,近年来,大多数年龄性别组的发病率似乎趋于稳定甚至下降。男性患者的发病率和死亡率继续高于女性患者,但无论男性还是女性患者,按部位计算增幅最大的是躯干。很大一部分黑色素瘤是在局部阶段被检测到的,厚度小于0.75毫米。

结论

建议预防阳光照射以扭转黑色素瘤的高发病率。

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