[干扰素组织拮抗作用对180/TG克罗克肿瘤生长的抑制作用：一种新型小鼠凝集素的鉴定]
[Inhibitory effect of the tissue antagonism of interferon on the development of 180/TG Crocker tumor: recognition of a new murine lectin].
作者信息
Chany-Fournier F, Pauloin A, Cerutti I, Chany C
出版信息
C R Acad Hebd Seances Acad Sci D. 1978 May 29;286(21):1551-3.
PMID:99261
Abstract
Crude and purified murine lectin preparations are extracted from costal cartilage (TAI). They inhibit the antiviral state induced by interferon. They also agglutinate the Crocker 180/TG tumor cells. After IP inoculation in mice, the purified lectin preparation significantly decreases tumor incidence and increases the animal's life span.
摘要
粗制和纯化的鼠凝集素制剂从肋软骨（TAI）中提取。它们抑制干扰素诱导的抗病毒状态。它们还能凝集克罗克180/TG肿瘤细胞。在小鼠体内进行腹腔注射接种后，纯化的凝集素制剂显著降低肿瘤发生率并延长动物寿命。
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