Méhes K, Bajnóczky K, Adamovich K, Khezri S, Kosztolányi G
Department of Paediatrics, University Medical School of Pécs, Hungary.
J Hum Genet. 1999;44(1):40-2. doi: 10.1007/s100380050104.
The possible effect of in vivo oxygen exposure on chromosomes was examined in lymphocyte cultures of 12 very-low-birthweight infants on the 1st, 8th, and 16th days of intensive care. No increase of cytogenetic anomalies was seen in untreated and bleomycin-treated cultures. The findings suggest that neonatal oxygen exposure is unlikely to cause latent chromosome damage.
在12名极低出生体重儿重症监护的第1天、第8天和第16天，对其淋巴细胞培养物中体内氧暴露对染色体的可能影响进行了检测。在未经处理和经博来霉素处理的培养物中均未发现细胞遗传学异常增加。研究结果表明，新生儿氧暴露不太可能导致潜在的染色体损伤。
