Richer J P, Lacoste L, Faure J P, Hauet T, Ferrié J C, Carretier M
Groupe de Recherche en Transplantations Multi-viscérales (GRTMV), INRA le Magneraud, Faculté de Médecine de Poitiers, France.
Surg Radiol Anat. 1998;20(6):431-5. doi: 10.1007/BF01653136.
The laboratory piglet is currently the preferred animal for experimental digestive surgery. In order to ensure optimal perioperative analgesic control with motor blockade during surgery together with rapid postoperative recovery, epidural anesthesia techniques were developed in this animal. We report the anatomo-radiologic studies (10 animals) and clinical experiments (51 transplantations of the liver and the small intestine) which led to the refinement of this anesthesia. In laboratory piglets, epidural anesthesia by distal transsacral (S4-S5) or sacrococcygeal approach is possible in a reproducible manner. The localization of the injection site is simple and epidural space catheterisation is easy without risk for the dural sac which ends at S1-S2.
目前，实验用仔猪是实验性消化外科手术的首选动物。为了确保手术期间能通过运动阻滞实现最佳的围手术期镇痛控制，并实现术后快速恢复，针对这种动物开发了硬膜外麻醉技术。我们报告了导致这种麻醉技术得以完善的解剖放射学研究（10只动物）和临床实验（51例肝脏和小肠移植手术）。在实验用仔猪中，通过经骶骨远端（S4-S5）或骶尾途径进行硬膜外麻醉是可行的，且具有可重复性。注射部位的定位简单，硬膜外腔置管容易，且不会对终止于S1-S2的硬脊膜囊造成风险。
