Umbert P, Winkelmann R K
J Cutan Pathol. 1976;3(2):75-87. doi: 10.1111/j.1600-0560.1976.tb00850.x.
Two cases of tubular apocrine adenoma were studied by light, histochemical, and electron microscopic methods. This benign apocrine hamartoma must be considered in the classification of appendage tumors, particularly those associated with organoid epithelial nevus, and may be confused with metastatic adenocarcinoma. The tumor is characterized by dermal and subcutaneous lobular masses of tubular structures. Connection to the epidermis by one or more ductlike structures is observed. The tubules contain typical apocrine epithelial cells, some with hyaline or clear cell differentiation. The tumor cells have apocrine differentiation by histochemistry and ultrastructure. The localization to the scalp and the nodular, lobulated appearance and the apocrine structures indicate that this tumor is similar to nevus syringocystadenoma papilliferum and must be diffentiated from it.
通过光镜、组织化学和电子显微镜方法对两例管状大汗腺腺瘤进行了研究。在附属器肿瘤的分类中，必须考虑这种良性大汗腺错构瘤，尤其是那些与器官样上皮痣相关的肿瘤，并且它可能与转移性腺癌相混淆。肿瘤的特征是真皮和皮下有管状结构的小叶状肿块。观察到通过一个或多个导管样结构与表皮相连。小管内含有典型的大汗腺上皮细胞，有些具有透明或透明细胞分化。肿瘤细胞通过组织化学和超微结构表现出大汗腺分化。肿瘤定位于头皮，呈结节状、分叶状外观以及大汗腺结构，表明该肿瘤与乳头状汗管囊腺瘤痣相似，必须与之鉴别。
