结直肠癌中癌症和腺瘤性息肉的分布情况。
Cancer and adenomatous polyp distribution in the colorectum.
作者信息
Ikeda Y, Mori M, Yoshizumi T, Sugimachi K
机构信息
Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
出版信息
Am J Gastroenterol. 1999 Jan;94(1):191-3. doi: 10.1111/j.1572-0241.1999.00795.x.
OBJECTIVE
To examine the possible role of adenomatous polyps in colorectal cancer development, this study focused on the relationship of the distribution between adenomatous polyps and cancer in the colorectum.
METHODS
The distribution of 753 adenomatous polyps was compared with that of 35 colorectal cancer lesions in 510 male patients ranging from 45 to 55 yr of age who underwent a total colonoscopy.
RESULTS
The incidence of cancer significantly increased with a distal shift in the colorectal sites in comparison with that of adenomatous polyps (p < 0.02).
CONCLUSION
The different distribution between adenomatous polyps and cancer thus suggested that adenomatous polyps at various colorectal sites appear to have a different malignant potential for cancer development.
目的
为研究腺瘤性息肉在结直肠癌发生中的可能作用，本研究聚焦于结直肠腺瘤性息肉与癌症的分布关系。
方法
对510例年龄在45至55岁之间接受全结肠镜检查的男性患者中753个腺瘤性息肉的分布与35个结直肠癌病灶的分布进行比较。
结果
与腺瘤性息肉相比，癌症发病率随结直肠部位向远端转移而显著增加（p < 0.02）。
结论
腺瘤性息肉与癌症的不同分布表明，结直肠不同部位的腺瘤性息肉在癌症发生方面似乎具有不同的恶性潜能。
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