近端结肠和远端结肠发生不同癌症的可能性：腺瘤性息肉与癌症分布的比较
Possibility of different cancer development between the proximal and distal colon: comparison of the distribution between adenomatous polyps and cancer.
作者信息
Ikeda Y, Mori M, Koyanagi N, Minagawa S, Kondo N, Fujimaru R, Kojima Y, Kondo A, Sugimachi K
机构信息
Department of Surgery II Faculty of Medicine, Kyushu University, Fukuoka, Japan.
出版信息
Hepatogastroenterology. 1998 Sep-Oct;45(23):1583-6.
BACKGROUND/AIM: The aim of this study was to compare the distribution of adenomatous polyps with that of cancer in the colon by using adenomatous polyps removed by colonoscopy.
METHODOLOGY
1223 adenomatous polyps removed by an endoscopic polypectomy were compared with 226 colon cancers with regard to their distribution, size and age.
RESULTS
With patients over 65 years of age, the incidence of adenomatous polyps was lower in the proximal colon than in the distal colon, however, the incidence of cancer was higher in the proximal colon than in the distal colon (p<0.05). The distribution of adenomatous polyps according to size was also significantly different between the proximal and distal colon (p<0.05).
CONCLUSION
These results thus suggest that some difference may exist in cancer development between the proximal and distal colon.
背景/目的：本研究的目的是通过使用结肠镜检查切除的腺瘤性息肉，比较结肠腺瘤性息肉与癌症的分布情况。
方法
将通过内镜息肉切除术切除的1223个腺瘤性息肉与226例结肠癌的分布、大小和年龄进行比较。
结果
在65岁以上的患者中，近端结肠腺瘤性息肉的发生率低于远端结肠，但近端结肠癌的发生率高于远端结肠（p<0.05）。近端和远端结肠腺瘤性息肉按大小的分布也有显著差异（p<0.05）。
结论
因此，这些结果表明近端和远端结肠在癌症发生方面可能存在一些差异。
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