精索静脉中的乳酸脱氢酶活性能否表明睾丸损伤？初步报告。

Can LDH activity in spermatic vein indicate testicular damage? A preliminary report.

作者信息

Odabaş O, Yilmaz Y, Atilla M K, Tarakçioğlu M, Aydin S

机构信息

Department of Urology, Medical School of Yüzüncü Yil University, Van, Turkey.

出版信息

Int Urol Nephrol. 1998;30(5):599-601. doi: 10.1007/BF02550552.

DOI:10.1007/BF02550552

PMID:9934804

Abstract

We aimed to investigate the relationship between varicocele and lactic dehydrogenase (LDH), an intracellular enzyme that indicates cellular damage. LDH levels were measured in the blood samples of 17 oligoasthenospermic infertile patients with varicocele which were obtained synchronously from spermatic and peripheral veins during operation. Sperm counts ranged from 1 to 74 million/ml, while motility ranged from 10% to 60%. LDH level in spermatic vein was found statistically higher than the level in peripheral vein (p = 0.042). There was no correlation between sperm counts and LDH level in spermatic vein. We found a significant increase in spermatic vein LDH level in varicocele. We think that further studies are needed to reveal the relationship between spermatic vein LDH level and varicocele.

摘要

我们旨在研究精索静脉曲张与乳酸脱氢酶（LDH，一种指示细胞损伤的细胞内酶）之间的关系。在17例患有精索静脉曲张的少弱精子症不育患者的血液样本中测量了LDH水平，这些样本是在手术期间同步从精索静脉和外周静脉获取的。精子计数范围为100万至7400万/ml，而活力范围为10%至60%。发现精索静脉中的LDH水平在统计学上高于外周静脉中的水平（p = 0.042）。精索静脉中的精子计数与LDH水平之间没有相关性。我们发现精索静脉曲张患者的精索静脉LDH水平显著升高。我们认为需要进一步研究以揭示精索静脉LDH水平与精索静脉曲张之间的关系。