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下颌成釉细胞瘤的保守性手术治疗

Conservative surgical treatment of mandibular ameloblastomas.

作者信息

Vedtofte P, Hjorting-Hansen E, Jensen B N, Roed-Peterson B

出版信息

Int J Oral Surg. 1978 Jun;7(3):156-61. doi: 10.1016/s0300-9785(78)80018-0.

DOI:10.1016/s0300-9785(78)80018-0
PMID:99379
Abstract

The results of a follow-up investigation of 12 patients with ameloblastomas of the mandible, treated by conservative surgical means, are presented. The age of the patients at the time of operation ranged from 8 to 77 years, the average age being 41 years. Seven of the tumors had a unilocular and five a multilocular appearance. The operation technique varied somewhat with the individual case. An attempt was made in all cases to remove the tumor in toto. In cases with multilocular appearance or where the tumor was in connection with the surface epithelium, a resection of the roof of the lesion was made. Microscopic examination of the tumors revealed that they all could be classified as plexiform or folicular but with various degrees of differentiation. Seven of the patients were observed for more than 5 years, the others for less. Three instances of recurrence were diagnosed and were in all cases less than 1 cm in diameter. The recurrences were found 1, 3, and 20 years after the primary treatment. Although the number of patients and the observation period are limited, the preliminary results seem encouraging.

摘要

本文介绍了12例采用保守手术方法治疗的下颌骨成釉细胞瘤患者的随访结果。患者手术时的年龄在8岁至77岁之间,平均年龄为41岁。其中7例肿瘤呈单房性,5例呈多房性。手术技术因个体病例而异。所有病例均试图完整切除肿瘤。对于多房性肿瘤或与表面上皮相连的肿瘤,进行了病变顶部的切除。肿瘤的显微镜检查显示,所有肿瘤均可分类为丛状或滤泡状,但分化程度不同。7例患者观察超过5年,其他患者观察时间较短。诊断出3例复发,所有复发病灶直径均小于1 cm。复发分别在初次治疗后1年、3年和20年发现。尽管患者数量和观察期有限,但初步结果似乎令人鼓舞。

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引用本文的文献

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Is conservative surgery a better choice for the solid/multicystic ameloblastoma than radical surgery regarding recurrence? A systematic review.就复发而言,对于实性/多囊性成釉细胞瘤,保守手术比根治性手术是更好的选择吗?一项系统评价。
Oral Maxillofac Surg. 2018 Dec;22(4):349-356. doi: 10.1007/s10006-018-0715-9. Epub 2018 Sep 6.
2
Ameloblastoma in the Northeast region of Brazil: A review of 112 cases.巴西东北部地区的成釉细胞瘤:112例病例回顾
J Oral Maxillofac Pathol. 2014 Sep;18(Suppl 1):S66-71. doi: 10.4103/0973-029X.141368.
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Surgical management of ameloblastoma: Conservative or radical approach.
成釉细胞瘤的外科治疗:保守还是根治方法。
Natl J Maxillofac Surg. 2011 Jan;2(1):22-7. doi: 10.4103/0975-5950.85849.
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Treatment of ameloblastoma of the jaws in children.儿童颌骨成釉细胞瘤的治疗
Ghana Med J. 2011 Mar;45(1):35-7. doi: 10.4314/gmj.v45i1.68921.
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[Comparison of clinical immunohistochemical findings in keratocystic odontogenic tumours and ameloblastomas considering their risk of recurrence].[考虑到角化囊性牙源性肿瘤和成釉细胞瘤的复发风险,对其临床免疫组化结果的比较]
Mund Kiefer Gesichtschir. 2007 Sep;11(4):221-31. doi: 10.1007/s10006-007-0068-2. Epub 2007 Jul 20.