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角膜保存过程中细胞膜状态及自溶机制的研究(作者译)

[Research on the state of the cell membrane and the mechanism of corneal autolysis in the conservation process (author's transl)].

作者信息

Trawkin A G, Gundorowa R A, Bordjugowa G G, Derewjanko W P, Zypin A B

出版信息

Klin Monbl Augenheilkd. 1976 Oct;169(4):500-4.

PMID:994408
Abstract

In this work we have thrown light on the basis of our experiments on 530 rabbits', dogs' and human eyes preserved under various conditions on the influence of antioxidation substances on corneal preservation. The development of autolysis is highly dependent on the absence of antioxident - also important for the survival of the cornea. From our results we have drawn conclusions regarding the participation of antioxidant (-tocopherol, chondroitin sulphate) on the self-regulating oxidation of structural lipids in the cell membranes of the cornea, and its effects on preservation.

摘要

在这项工作中,我们基于对530只兔子、狗和人类眼睛在各种条件下保存的实验,揭示了抗氧化物质对角膜保存的影响。自溶的发展高度依赖于抗氧化剂的缺失——这对角膜的存活也很重要。从我们的结果中,我们得出了关于抗氧化剂(维生素E、硫酸软骨素)参与角膜细胞膜结构脂质的自我调节氧化及其对保存效果的结论。

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