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[不同抗自由基活性抗氧化剂对角膜保存的影响]

[Effect of antioxidants with different antiradical activity on cornea preservation].

作者信息

Travkin A G, Vinetskaia M I, Slepukhina L V

出版信息

Biofizika. 1976 Nov;21(6):1064-6.

PMID:1009199
Abstract

Changes of chemoluminescence intensity, collagen mucopolysaccaride content in the rabbit eye cornea were studied on 32 cornea of shinshilla eye conservated by dehydration under hipotenia (2 divided by 4 degrees C) for 60 days with the application of antioxidants (tocoferol, chlorhydrate 2-ethyl, 6-methyl-3-oxipyridine) having different antiradical activity. It is concluded that the application of natural antioxidant alpha-tocoferol having high antiradical activity is expedient for the conservation of cornea.

摘要

在2至4摄氏度低眼压条件下对32只新罗兔眼的角膜进行脱水保存60天,并应用具有不同抗自由基活性的抗氧化剂(生育酚、2-乙基-6-甲基-3-氧代吡啶盐酸盐),研究兔眼角膜化学发光强度、胶原粘多糖含量的变化。得出结论:应用具有高抗自由基活性的天然抗氧化剂α-生育酚对角膜保存是适宜的。

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