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腹腔镜肾上腺切除术治疗原发性醛固酮增多症:12例临床经验

Laparoscopic adrenalectomy for primary aldosteronism: clinical experience in 12 patients.

作者信息

Sirén J, Haglund C, Huikuri K, Sivula A, Haapiainen R

机构信息

Department of Surgery, Helsinki University Central Hospital, Finland.

出版信息

Surg Laparosc Endosc. 1999 Jan;9(1):9-13.

PMID:9950120
Abstract

Laparoscopic adrenalectomy has become a viable option for removal of small adrenal neoplasms. We present our initial experience of this operation for primary aldosteronism. In this prospective study, 12 consecutive patients with primary aldosteronism were operated on laparoscopically by one surgeon. Operative time, blood loss, postoperative pain, complications, hospital stay, convalescence time, and outcome were analyzed. Five right-sided and seven left-sided adrenalectomies were performed in six female and six male patients with a mean age of 51 years. The mean operative time was 126 minutes. All procedures were successfully carried out laparoscopically. No major complications occurred. All patients turned normokalemic and the medication for hypertension could be stopped or diminished in all cases. The mean hospital stay was 3.4 days, and the mean sick leave was 13 days. Laparoscopic adrenalectomy seems to be a safe and effective treatment for primary aldosteronism and should be considered the operation of choice.

摘要

腹腔镜肾上腺切除术已成为切除肾上腺小肿瘤的一种可行选择。我们展示了我们开展该手术治疗原发性醛固酮增多症的初步经验。在这项前瞻性研究中,由一名外科医生对12例连续性原发性醛固酮增多症患者进行了腹腔镜手术。分析了手术时间、失血量、术后疼痛、并发症、住院时间、康复时间及治疗效果。对6例女性和6例男性患者实施了5例右侧和7例左侧肾上腺切除术,平均年龄51岁。平均手术时间为126分钟。所有手术均成功通过腹腔镜完成。未发生重大并发症。所有患者血钾恢复正常,所有病例中治疗高血压的药物均可停用或减量。平均住院时间为3.4天,平均病假为13天。腹腔镜肾上腺切除术似乎是治疗原发性醛固酮增多症的一种安全有效的方法,应被视为首选手术方式。

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