增塑聚氯乙烯对血液的影响：增塑剂的意义
Influence on blood of plasticized polyvinyl chloride: significance of the plasticizer.
作者信息
Zhao X, Courtney J M
机构信息
Bioengineering Unit, University of Strathclyde, Glasgow, United Kingdom.
出版信息
Artif Organs. 1999 Jan;23(1):104-7. doi: 10.1046/j.1525-1594.1999.06267.x.
An investigation has been made of the significance of the level of the plasticizer di-(2-ethylhexyl)phthalate at the surface of plasticized polyvinyl chloride for interactions with blood components. Plasticized polyvinyl chloride before and after treatment with methanol to reduce the plasticizer surface level was assessed in terms of fibrinogen and albumin adsorption with unplasticized polyvinyl chloride acting as a control. As the plasticizer surface level decreased, fibrinogen adsorption decreased almost linearly while albumin adsorption increased initially before decreasing slightly. The investigation indicates that reduction in the amount of plasticizer at the surface improves the blood compatibility of plasticized polyvinyl chloride, and the influence on blood is due primarily to the plasticizer rather than the polyvinyl chloride itself.
已对增塑聚氯乙烯表面的增塑剂邻苯二甲酸二（2-乙基己基）酯水平对于与血液成分相互作用的重要性进行了研究。用甲醇处理以降低增塑剂表面水平前后的增塑聚氯乙烯，就纤维蛋白原和白蛋白吸附情况进行了评估，未增塑的聚氯乙烯用作对照。随着增塑剂表面水平降低，纤维蛋白原吸附几乎呈线性下降，而白蛋白吸附最初增加，之后略有下降。该研究表明，表面增塑剂含量的减少改善了增塑聚氯乙烯的血液相容性，对血液的影响主要归因于增塑剂而非聚氯乙烯本身。
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