Mo C N, Ladusans E J
Department of Paediatric Cardiology, Royal Manchester Children's Hospital, UK.
J Med Genet. 1999 Jan;36(1):83-4.
Two cases are reported of fetal valproate syndrome in association with anomalous right pulmonary artery origin. Both diagnoses were confirmed following cardiac catheterisation as echocardiography alone was inadequate to define the anatomy. Anomalous right pulmonary artery origin is extremely rare making a chance association with fetal valproate syndrome very unlikely. We recommend that anomalous pulmonary artery origin is borne in mind in patients with valproate syndrome undergoing cardiac assessment, particularly as this may be a difficult diagnosis to make on echocardiography.
报告了两例胎儿丙戊酸综合征合并右肺动脉起源异常的病例。在心脏导管插入术后，两种诊断均得到证实，因为仅靠超声心动图不足以明确解剖结构。右肺动脉起源异常极为罕见，因此与胎儿丙戊酸综合征偶然相关的可能性极小。我们建议，在对丙戊酸综合征患者进行心脏评估时，应考虑到肺动脉起源异常的情况，尤其是因为这在超声心动图上可能是一个难以做出的诊断。
