de la Cuétara-Bernal K
Departamento de Cultivo de Tejido Nervioso, Centro Internacional de Restauración Neurológica (CIREN), La Habana, Cuba.
Rev Neurol. 1998 Dec;27(160):1043-9.
The moral-ethical problem of the use of human embryos as a source of cells for neurotransplants involves serious conflicts as to which tissues to use, from which source, what method should be used to obtain them and also the search for alternative sources of tissues.
In this paper we present a brief summary of ethical and medical points involved in the obtention, protection of the donor, preparation, safety and efficacy of human foetal nervous tissue in the context of neural transplants. The ethics of human foetal nervous tissue are very complex in that they represent a dilemma involving several points of medical ethics, which are themselves very controversial, including abortion, transplants and incorporation in the cerebral function of an individual. From a bioethical point of view, we consider aspects such as the establishment of an optimal source for obtention of nervous tissue for transplants, the safety and efficacy of this, informed consent for donation of tissue, availability and storage among other aspects.
All programmes that envisage the use of foetal tissue for the purpose of transplants should strictly and truly conform to local and national ethical regulations before starting clinical trials.
将人类胚胎作为神经移植细胞来源所涉及的道德伦理问题，在使用何种组织、组织来源、获取组织的方法以及寻找替代组织来源等方面存在严重冲突。
在本文中，我们简要概述了在神经移植背景下，获取人类胎儿神经组织所涉及的伦理和医学要点、供体保护、制备、安全性和有效性。人类胎儿神经组织的伦理问题非常复杂，因为它们代表了一个涉及多个医学伦理要点的困境，而这些要点本身就极具争议性，包括堕胎、移植以及个体脑功能的纳入。从生物伦理学角度来看，我们考虑了诸如为移植获取神经组织建立最佳来源、其安全性和有效性、组织捐赠的知情同意、可用性和储存等方面。
所有设想将胎儿组织用于移植目的的项目，在开始临床试验之前，都应严格且切实地符合当地和国家的伦理法规。
