Knudsen B B
Dermato-venerologisk afdeling K, Amtssygehuset i Gentofte.
Ugeskr Laeger. 1999 Jan 25;161(4):431-5.
This study gives a descriptive analysis of 52 patients with type-I allergy to latex. Seventy-one percent of these cases were considered occupational, especially related to the health care sector (29 of 37 patients). Four patients had to change their jobs because of the allergy. Twenty-five percent presented initially with monosymptomatic contact urticaria, while 35% presented with hand eczema, which could only be explained by concomitant allergy to rubber chemicals in 35% of the cases. During the period from observation of initial symptoms until establishment of the diagnosis, several of the patients with monosymptomatic hand eczema developed additional type-I related symptoms. Not only latex-exposed patients with type-I-related symptoms, but also latex-exposed patients with hand eczema should be suspected for latex-allergy and tested with pricktests, latex-specific IgE and skin-provocation tests.
本研究对52例对乳胶I型过敏的患者进行了描述性分析。其中71%的病例被认为与职业有关，特别是与医疗保健行业相关（37例患者中有29例）。4名患者因过敏不得不更换工作。25%的患者最初表现为单症状性接触性荨麻疹，而35%的患者表现为手部湿疹，其中35%的病例只能用对橡胶化学品的伴随过敏来解释。在从观察初始症状到确诊的期间，几名单症状性手部湿疹患者出现了其他I型相关症状。不仅有I型相关症状的乳胶暴露患者，而且有手部湿疹的乳胶暴露患者都应怀疑对乳胶过敏，并进行点刺试验、乳胶特异性IgE和皮肤激发试验。
