Ferrigno L, Belpoliti M, Carta A, Rosmini F, Maraini G
Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy.
Ophthalmology. 1999 Feb;106(2):232-5. doi: 10.1016/S0161-6420(99)90061-1.
To evaluate whether, in the Italian-American natural history study, cataract surgery in one eye influences the incidence/progression rate of lens opacities in the fellow eye.
Follow-up study of age-related cataract.
A total of 1399 participants with age-related cataracts were regularly followed for 5 years and cataract status evaluated by the Lens Opacities Classification System II on slit-lamp and retroillumination lens photographs. A total of 228 participants had cataract surgery in 1 eye during the study period, and 192 had sufficient follow-up visits to be included in the analysis.
The incidence/progression of cataract was defined as two or more consecutive visits with a severity grade greater than the baseline grade.
When entered into a Cox model, incidence/progression of specific cataract types was not associated with cataract surgery on the fellow eye and was not significantly different from that observed in participants who had no cataract surgery.
Cataract extraction does not influence incidence/progression rate of specific lens opacities in the fellow eye.
在意大利裔美国人自然病史研究中，评估一只眼睛进行白内障手术是否会影响另一只眼睛晶状体混浊的发生率/进展率。
年龄相关性白内障随访研究。
总共1399名年龄相关性白内障参与者接受了为期5年的定期随访，并通过裂隙灯和后照法晶状体照片，采用晶状体混浊分类系统II评估白内障状态。在研究期间，共有228名参与者一只眼睛进行了白内障手术，192名有足够的随访次数可纳入分析。
白内障的发生率/进展定义为连续两次或更多次就诊时严重程度等级高于基线等级。
纳入Cox模型时，特定类型白内障的发生率/进展与另一只眼睛的白内障手术无关，与未进行白内障手术的参与者所观察到的情况无显著差异。
白内障摘除术不会影响另一只眼睛特定晶状体混浊的发生率/进展率。
