Browning D J, Antoszyk A N
Charlotte Eye, Ear, Nose, and Throat Associates, North Carolina, USA.
Ophthalmology. 1999 Feb;106(2):243-8. doi: 10.1016/S0161-6420(99)90063-5.
To determine the effect of the surgeon and the wavelength of laser used on the response to focal photocoagulation for diabetic macular edema.
Retrospective case-control study.
Forty-four matched pairs of cases by two different retina surgeons in the study of surgeon influence were examined. Sixty-nine matched pairs of cases using dye yellow versus argon green laser treatment in the study of wavelength influence also were studied. In both studies, eyes were matched for the only patient-dependent variables affecting outcome: age, initial visual acuity, follow-up time, and diabetic control by diet versus any other method.
Focal laser photocoagulation for clinically significant diabetic macular edema was performed.
Visual acuity at 6 months follow-up was measured.
For the study in which the only difference was the surgeon, at 6 months follow-up the mean difference in logarithm of the minimum angle of resolution (logMAR) visual acuity was -0.045, 95% confidence interval (-0.160, 0.070). For the study in which wavelength varied, at 6 months the mean difference in logMAR visual acuity was -0.048, 95% confidence interval (-0.147, 0.052). The power of the surgeon study to detect a difference in the logMAR visual acuity of 0.3 is 88% and of the wavelength study to detect this difference is 99%.
In looking at the 6-month visual outcome after focal laser photocoagulation for clinically significant diabetic macular edema, different fellowship trained surgeons and the choice of green or yellow wavelength had no effect on the treatment outcome.
确定外科医生及所用激光波长对糖尿病性黄斑水肿局灶性光凝反应的影响。
回顾性病例对照研究。
在外科医生影响研究中,对由两位不同视网膜外科医生治疗的44对匹配病例进行了检查。在波长影响研究中,还对69对使用染料黄激光与氩绿激光治疗的匹配病例进行了研究。在两项研究中,根据影响结果的仅有的患者相关变量对眼睛进行匹配:年龄、初始视力、随访时间以及饮食控制糖尿病与其他任何方法控制糖尿病的情况。
对具有临床意义的糖尿病性黄斑水肿进行局灶性激光光凝。
测量随访6个月时的视力。
在仅外科医生不同的研究中,随访6个月时,最小分辨角对数视力(logMAR)的平均差值为-0.045,95%置信区间为(-0.160,0.070)。在波长不同的研究中,随访6个月时,logMAR视力的平均差值为-0.048,95%置信区间为(-0.147,0.