Araya Araya J, Rojas García M, Fernández Fraile P, Mateluna Acevedo A
Universidad de Chile, San José.
Arch Latinoam Nutr. 1998 Sep;48(3):210-5.
The content and distribution of long-chain polyunsaturated fatty acids (LCP) of maternal-fetal erythrocytes phospholipids was investigated. Blood samples from healthy pregnant women were taken from maternal veins and umbilical cord at spontaneous delivery time. Two groups were segregated and compared in terms of fetuses gestational age: preterm delivery (32-34 weeks) and term delivery (40 weeks). The results showed that in erythrocytes of term newborn the content of LCP omega 6 and omega 3; particularly 20:4w6 (ARA) and 22:6w3 (DHA), were found to be statistically higher than their respective mother. However, in preterm newborns, all LCP from phospholipids erythrocytes were found to be statistically lower than in their mother. Comparing the content of ARA and DHA between the newborn groups, it observed that only DHA was decreased in preterm group. Women who delivered premature babies showed a blood ratio ARA/DHA higher than those who delivered term-babies. From this study and considering previous information it can be suggested that a high content of ARA and ARA/DHA ratio in maternal and fetal erythrocytes may considered an early risk signal of preterm delivery.
对母胎红细胞磷脂中长链多不饱和脂肪酸(LCP)的含量及分布进行了研究。在自然分娩时,从健康孕妇的母静脉和脐带采集血样。根据胎儿孕周将两组进行分离和比较:早产(32 - 34周)和足月分娩(40周)。结果显示,足月新生儿红细胞中LCPω6和ω3的含量,特别是20:4ω6(花生四烯酸,ARA)和22:6ω3(二十二碳六烯酸,DHA),在统计学上高于各自的母亲。然而,早产新生儿红细胞磷脂中的所有LCP在统计学上均低于其母亲。比较新生儿组之间的ARA和DHA含量,发现早产组中只有DHA降低。早产产妇的血液ARA/DHA比值高于足月产产妇。从这项研究并结合先前的信息可以推测,母胎红细胞中高含量的ARA和ARA/DHA比值可能被视为早产的早期风险信号。