Gupta R K, Green C, Naran S, Lallu S, Fauck R, Dowle C, Simpson J
Cytology Unit, Wellington Hospital, New Zealand.
Diagn Cytopathol. 1999 Feb;20(2):82-4. doi: 10.1002/(sici)1097-0339(199902)20:2<82::aid-dc8>3.0.co;2-0.
Adenoid cystic carcinoma (ACC) of the breast is a rare variant of breast malignancy and has a better prognosis than its counterpart in the salivary glands. In this communication, our experience with seven cases of ACC of the breast is presented in which the diagnosis was established on fine-needle aspiration cytology (FNAC). The cytologic samples in all cases were cellular and featured three-dimensional clusters of uniform ductal epithelial cells with cystic spaces, bland nuclei, fine chromatin, and scanty cytoplasm arranged around spheres or cores of homogenous material. The cytodiagnosis of ACC in all cases correlated with subsequent examination of cell blocks of the aspirate and tissue. The cytodiagnostic criteria for ACC of the breast which are useful in a correct FNAC diagnosis are discussed.
乳腺腺样囊性癌（ACC）是一种罕见的乳腺恶性肿瘤变体，其预后比唾液腺的同类肿瘤要好。在本报告中，我们介绍了7例乳腺ACC的病例，这些病例均通过细针穿刺细胞学检查（FNAC）确诊。所有病例的细胞学样本均有细胞，其特征为均匀的导管上皮细胞呈三维簇状排列，伴有囊性间隙，细胞核温和，染色质细腻，细胞质稀少，围绕着均质物质的球体或核心排列。所有病例中ACC的细胞诊断与随后对穿刺物和组织的细胞块检查结果相符。本文讨论了有助于正确FNAC诊断的乳腺ACC的细胞诊断标准。
