Sundelin K, Sjöstrand J
Department of Ophthalmology, Sahlgrenska University Hospital, Gothenburg, Sweden.
J Cataract Refract Surg. 1999 Feb;25(2):246-50. doi: 10.1016/s0886-3350(99)80134-5.
To find out whether there is a "hidden" group of patients with posterior capsule opacification (PCO) 5 years after cataract surgery and to establish the incidence of PCO.
Department of Ophthalmology, Sahlgrenska University Hospital, Gothenburg, Sweden.
A random sample (n = 164) was selected among patients who had extracapsular cataract extraction (ECCE) with intraocular lens implantation in 1991 (N = 1672). All surgically treated cases that required neodymium:YAG (Nd:YAG) laser capsulotomy (n = 37) within the first 5 years after surgery were recorded. Patients still alive 5 years after surgery who had not had Nd:YAG treatment were offered an eye examination to determine whether PCO requiring capsulotomy existed.
Thirty-seven of 110 patients (34%) alive 5 years after surgery had an Nd:YAG capsulotomy during the first 5 postoperative years. Follow-up was possible in 51 of 73 untreated patients (70%). Clinically significant PCO according to specified criteria was found in 7 cases (14%). Half of them would benefit from treatment; the other half had visual impairment from other eye disease.
The estimated incidence of PCO 5 years after ECCE was 43%. Five years after surgery, there was an untreated group with clinically significant PCO, approximately 9% of the surgically treated population. This hidden group must be considered in PCO studies.
了解白内障手术后5年是否存在后囊膜混浊(PCO)的“隐匿”患者群体,并确定PCO的发生率。
瑞典哥德堡萨尔格伦斯卡大学医院眼科。
从1991年接受囊外白内障摘除术(ECCE)并植入人工晶状体的患者中随机抽取样本(n = 164)(N = 1672)。记录所有在术后前5年内需要钕:钇铝石榴石(Nd:YAG)激光囊膜切开术的手术治疗病例(n = 37)。对术后5年仍存活且未接受Nd:YAG治疗的患者进行眼科检查,以确定是否存在需要进行囊膜切开术的PCO。
术后5年存活的110例患者中有37例(34%)在术后前5年内接受了Nd:YAG囊膜切开术。73例未治疗患者中有51例(70%)接受了随访。根据特定标准,发现7例(14%)患者存在具有临床意义的PCO。其中一半患者将从治疗中受益;另一半患者因其他眼部疾病导致视力受损。
ECCE术后5年PCO的估计发生率为43%。术后5年,存在一组未接受治疗且具有临床意义的PCO患者,约占手术治疗人群的9%。在PCO研究中必须考虑这一隐匿群体。