Irie H, Satoh H, Akama T, Yamashita Y T, Ishikawa H, Ohtsuka M
Department of Respiratory Medicine, University of Tsukuba, Japan.
Med Oncol. 1998 Dec;15(4):289-91. doi: 10.1007/BF02787216.
The association between systemic lupus erythematosus (SLE) and malignancy has been controversial in the literature. We report a case of lung cancer in a 50-year-old woman with a 4-year history of SLE. She underwent surgery at a pathological stage of T2N2M0, but she eventually died of rapid recurrence of the cancer in the abdomen resulting in massive haemorrhage from the inferior vena cava (IVC). Immunological disorders related to SLE are thought to contribute to rapid progression of the malignancy.
系统性红斑狼疮（SLE）与恶性肿瘤之间的关联在文献中一直存在争议。我们报告一例50岁患有4年SLE病史的女性肺癌病例。她在病理分期为T2N2M0时接受了手术，但最终死于腹部癌症的快速复发，导致下腔静脉（IVC）大量出血。与SLE相关的免疫紊乱被认为促成了恶性肿瘤的快速进展。
