Kigawa J, Kanamori Y, Takeuchi Y, Minagawa Y, Terakawa N
Department of Obstetrics and Gynecology, Tottori University School of Medicine, Yonago, Japan.
Gynecol Obstet Invest. 1993;36(1):62-4. doi: 10.1159/000292597.
Although patients with systemic lupus erythematosus (SLE) have frequently accompanying malignancies, there are few documented cases in the literature of advanced cervical cancer patients with SLE. This report describes a case of advanced cervical cancer in a 39-year-old patient with a 20-year history of SLE (FIGO stage IIIb) and evaluates the immunological response of the tumor. The clinical course of this patient with SLE, with rapid growth of cervical cancer and a poor prognosis, may suggest that T cells play a key role in the growth of cancer.
尽管系统性红斑狼疮(SLE)患者常伴有恶性肿瘤,但文献中记录的晚期宫颈癌合并SLE的病例很少。本报告描述了一名39岁、有20年SLE病史的晚期宫颈癌患者(国际妇产科联盟分期IIIb期),并评估了肿瘤的免疫反应。该SLE患者宫颈癌生长迅速且预后不良的临床过程可能提示T细胞在癌症生长中起关键作用。