Amato G, Martella A, Ferraraccio F, Di Martino N, Maffettone V, Landolfi V, Fei L, Del Genio A
Second University of Naples, School of Medicine, Institute of General Surgery and Surgical Therapy, Department of Digestive Diseases, Italy.
Hepatogastroenterology. 1998 Nov-Dec;45(24):2151-6.
Liposarcoma is the second most common soft tissue sarcoma in adults. These neoplasms take their origin from primitive mesenchymal cells and are rarely encountered in fat rich areas, such as subcutaneous tissue and/or the subserosa of the intestinal tract which, on the contrary, are the two most common sites of lipomas. The two major locations of liposarcomas are the extremities and the retroperitoneum followed with much less frequency by the inguinal region. Other sites are uncommon, particularly the mesentery (9 cases to date in the literature) and, even more so, the mesocolon (only 3 cases of primary sarcoma of the mesocolon reported to date). This paper reports on the case of a well differentiated "lipoma-like" liposarcoma of the sigmoid mesocolon, associated with multiple lipomatosis of the recto-sigmoid colon in a 75 year-old female patient. Surgical treatment consisted of a trans-anal extra-peritoneal anterior resection by CEEA 28 stapler under endoscopic vision. The patient has been followed up for the last 2 years and is still disease-free and well. The peculiarity of the case consists in the contemporaneous presence in close contiguity of two different rare neoplasms whose association is not yet known.
脂肪肉瘤是成人中第二常见的软组织肉瘤。这些肿瘤起源于原始间充质细胞，在富含脂肪的区域很少见，如皮下组织和/或肠道浆膜下层，而这两个部位恰恰是脂肪瘤最常见的两个部位。脂肪肉瘤的两个主要发病部位是四肢和腹膜后，腹股沟区的发病频率则低得多。其他部位不常见，尤其是肠系膜（迄今为止文献报道9例），乙状结肠系膜更少见（迄今为止仅报道3例原发性乙状结肠系膜肉瘤）。本文报告了一例75岁女性患者，其乙状结肠系膜发生高分化“脂肪瘤样”脂肪肉瘤，并伴有直肠乙状结肠多发脂肪瘤病。手术治疗采用经肛门内镜直视下用CEEA 28吻合器行腹膜外前路切除术。该患者已随访2年，目前仍无病且状况良好。该病例的独特之处在于，两种不同的罕见肿瘤紧密相邻同时存在，其关联性尚不清楚。
