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钠转运抑制对蟾蜍膀胱活性磷酸盐转运的影响。

Effect of sodium transport inhibition on active phosphate transport by toad bladder.

作者信息

Sellers B B, Hall J A, Mendoza S A

出版信息

J Membr Biol. 1978 Jul 18;41(4):323-8. doi: 10.1007/BF01871996.

Abstract

The relationship between active Na transport (estimated by the short-circuit (SCC)) and active inorganic phosphate (Pi) transport was studied in the toad bladder. When SCC was inhibited by amiloride, ouabain, or removal of K from the serosal bathing solution, active Pi transport was totally inhibited. When Na was replaced isotonically by choline in either the mucosal bathing solution or both the mucosal and serosal bathing solutions, there was no measurable SCC or active Pi transport. These experiments are compatible with the hypothesis that active Pi transport occurs only in the presence of active Na transport.

摘要

在蟾蜍膀胱中研究了主动钠转运(通过短路电流(SCC)估算)与主动无机磷酸盐(Pi)转运之间的关系。当SCC被氨氯吡脒、哇巴因抑制,或从浆膜侧浴液中去除钾时,主动Pi转运被完全抑制。当在黏膜侧浴液或黏膜侧和浆膜侧浴液中用胆碱等渗替代钠时,未检测到SCC或主动Pi转运。这些实验与主动Pi转运仅在主动钠转运存在时发生这一假说相符。

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