Greco A V, Ghirlanda G, Rebuzzi A, Altomonte L, Manna R
Minerva Med. 1976 Nov 10;67(54):3525-32.
Cirrhotics presented higher insulin production, in the presence of a drop in glycaemia significantly less than controls, following 1 g of tolbutamide i.v. The drug also brought on a rapid drop in NEFA and a rise in plasma growth hormone. The pathogenesis of altered glucose tolerance in liver cirrhosis is discussed.
肝硬化患者在静脉注射1克甲苯磺丁脲后，胰岛素分泌增加，血糖下降幅度明显小于对照组。该药物还使游离脂肪酸迅速下降，血浆生长激素升高。文中讨论了肝硬化患者糖耐量改变的发病机制。
