Boudouresques J, Toga M, Khalil R, Chérif A A, Pellissier J F, Gosset A
Rev Neurol (Paris). 1976 Sep;132(9):623-37.
Anatomo-clinical findings are reported in a case of central nervous system degeneration which began at age 47 and progressed over a three year period. Information obtained prior to the patient's death suggested probable spinocerebellar degeneration with amyotrophies. Postmortem anatomical examination confirmed this diagnosis but also revealed the existence of unsuspected lesions. These clinically non-manifested lesions involved severe pallido-luysian degeneration as well as numerous and diffuse senile plaques. The nosological implications of this case are discussed.
报告了一例中枢神经系统变性病例的解剖学临床发现，该病例始于47岁，病程长达三年。患者死亡前获得的信息提示可能为伴有肌萎缩的脊髓小脑变性。尸检解剖证实了这一诊断，但也发现了意外病变。这些临床上未表现出的病变包括严重的苍白球-路易体变性以及大量弥漫性老年斑。讨论了该病例的疾病分类学意义。
