Ammann R, Deyhle P, Sulser H
Schweiz Med Wochenschr. 1976 Jun;106(26):894-7.
A kindred of "minor adenomatous polyposis" associated with a high incidence of gastric cancer is described. Five out of 14 mainly asymptomatic individuals in 2 generations of kindred examined clinically, by panendoscopy and coloscopy exhibited multiple polyps of colon or/and stomach and jejunum. Single or multiple papillary adenomas were detected mainly in the right or middle colon (3 times or in the jejunum (once). Hyperplastic polyps were found in the stomach (3 times) and in the colon (twice of these 5 individuals. Our findings suggest that "minor adenomatous polyposis" associated with gastric cancer may represent another, hitherto unrecognized, phenotype of familial multiple polyposis.
本文描述了一种与胃癌高发相关的“轻度腺瘤性息肉病”家族。在接受临床检查、全内镜检查和结肠镜检查的两代家族中，14名主要无症状个体中有5人出现了结肠、胃和空肠的多发性息肉。主要在右半结肠（3例）或空肠（1例）检测到单个或多个乳头状腺瘤。增生性息肉在胃中发现3例，在结肠中发现2例（这5例中有2例）。我们的研究结果表明，与胃癌相关的“轻度腺瘤性息肉病”可能代表了家族性多发性息肉病的另一种迄今未被认识的表型。
