Peltre G
CNRS-Institut Pasteur-28, Paris.
Allerg Immunol (Paris). 1998 Dec;30(10):324-6.
Morbidity to pollens is increasing in the French population. Pollen is the vector of the male genome of the plant. It is the wind-borne pollens that are the most allergenic by release of allergen molecules that make contact with the mucosae. So every individual who is genetically allergic (atopic) may develop rhinitis and/or conjunctivitis and/or asthma.... More than 200 allergens have been identified, of which the three-dimensional structure is well-known. The urban pollution that is specific to a quarter under consideration (residential zone, pedestrianised, mid-town roadway and industrial zone) plays an important role in morbidity to pollen allergy. A significant coating of pollens is to be found on urban roads. Pollen sensitisation is increased by exposure to pollutants from 24 to 48 hours. The pollutants seem to make the surface of the exine more fragile, so triggering a mucosal reaction, making them more exposed to pollen allergens. The pollutant also plays the role of an adjuvant to the pollen allergen, and so is the origin of a greater production of IgE.
法国人群中对花粉的过敏发病率正在上升。花粉是植物雄性基因组的载体。通过释放与黏膜接触的过敏原分子，风媒花粉具有最强的致敏性。因此，每个具有遗传易感性（特应性）的个体都可能患上鼻炎和/或结膜炎和/或哮喘……已鉴定出200多种过敏原，其中三维结构已为人所知。特定区域（住宅区、步行区、市中心道路和工业区）特有的城市污染在花粉过敏发病率中起着重要作用。在城市道路上可发现大量花粉附着。接触污染物24至48小时会增加花粉致敏性。污染物似乎使花粉外壁表面更脆弱，从而引发黏膜反应，使机体更容易接触花粉过敏原。污染物还起到花粉过敏原佐剂的作用，因此是产生更多IgE的原因。
