Spaulding A, Greene C, Davidson K, Schneidermann M, Rich J
Division of Infectious Disease, Rhode Island Hospital, Providence, USA.
Prev Med. 1999 Jan;28(1):92-100. doi: 10.1006/pmed.1998.0418.
No previous studies have examined the extent to which correctional facilities in the United States screen for and treat hepatitis C (HCV) infection.
Medical directors of state correctional facilities responded to a survey assessing the degree to which prisons screen for and treat hepatitis C. To estimate numbers of inmates eligible for interferon treatment and to examine costs associated with HCV management, we constructed a feasibility model that incorporated screening criteria used in California and Rhode Island.
Thirty-six states and Washington, DC, responded, resulting in a survey response rate of 73%, representing 77% of all inmates in state facilities nationwide. Colorado alone reported routine screening. Only California reported conducting a systematic seroprevalence study, which found that 39.4% of male inmates were hepatitis C antibody positive in 1994. Seventy-three percent of the respondents sometimes consider treating with interferon. Four states follow a standard protocol. The feasibility model suggests that treating suitably screened inmates is a reasonable expenditure for correctional systems.
Prison may be an appropriate setting for treatment of hepatitis C. If accompanying substance abuse issues are addressed, instituting HCV treatment for certain eligible incarcerated individuals may be a worthy target for public health dollars.
此前尚无研究调查美国惩教机构对丙型肝炎(HCV)感染进行筛查和治疗的程度。
州惩教机构的医疗主任对一项调查做出回应,该调查评估了监狱对丙型肝炎进行筛查和治疗的程度。为了估计符合干扰素治疗条件的囚犯人数,并研究与HCV管理相关的成本,我们构建了一个可行性模型,纳入了加利福尼亚州和罗德岛州使用的筛查标准。
36个州和华盛顿特区做出了回应,调查回复率为73%,占全国州立设施中所有囚犯的77%。仅科罗拉多州报告了常规筛查。只有加利福尼亚州报告进行了系统的血清流行率研究,该研究发现1994年39.4%的男性囚犯丙型肝炎抗体呈阳性。73%的受访者有时会考虑使用干扰素进行治疗。四个州遵循标准方案。可行性模型表明,对经过适当筛查的囚犯进行治疗对惩教系统来说是一项合理的支出。
监狱可能是治疗丙型肝炎的合适场所。如果同时解决伴随的药物滥用问题,为某些符合条件的被监禁个体开展HCV治疗可能是公共卫生资金的一个有价值的目标。