与克隆性CD8 + T细胞大颗粒淋巴细胞增多症相关的纯红细胞再生障碍：对环孢素A治疗的依赖性。
Pure red cell aplasia associated to clonal CD8+ T-cell large granular lymphocytosis: dependence on cyclosporin A therapy.
作者信息
Coutinho J, Lima M, dos Anjos Teixeira M, Cabeda J M, Leite F, Justiça B
机构信息
Service of Clinical Haematology, St. Antonio's Hospital, Porto, Portugal.
出版信息
Acta Haematol. 1998;100(4):207-10. doi: 10.1159/000040906.
PMID:9973645
Abstract
This case report details a single patient with pure red cell aplasia (PRCA) associated with clonal CD3+, TCRalphabeta+, TCR-Vbeta8+, CD8+, CD57+ large granular lymphocytosis whose anaemia did not respond to conventional immunosuppressive therapy but did respond to cyclosporin A (CsA). The patient has become dependent on CsA for 7 years in order to control anaemia due to associated PRCA.
摘要
本病例报告详细介绍了一名患有纯红细胞再生障碍性贫血（PRCA）并伴有克隆性CD3 +、TCRαβ +、TCR-Vβ8 +、CD8 +、CD57 +大颗粒淋巴细胞增多症的患者，其贫血对传统免疫抑制治疗无反应，但对环孢素A（CsA）有反应。为控制因相关PRCA导致的贫血，该患者已依赖CsA达7年。
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