Gautier A, Pouplard F, Bednarek N, Motte J, Berquin P, Billard C, Boidein F, Boulloche J, Dulac O, Echenne B, Humbertclaude V
Unité de neuropédiatrie, département de pédiatrie médicale, centre Robert-Debré, CHU, Angers, France.
Arch Pediatr. 1999 Jan;6(1):32-9. doi: 10.1016/s0929-693x(99)80070-0.
Benign infantile non febrile seizures are not well known, leading us to study their clinical and EEG characteristics.
Between 1981 and 1994, we assembled 34 patients with the following inclusion criteria: non febrile seizures between 1 month and 2 years of age, normal personal history, no abnormality on clinical, biological and radiological investigations, normal developmental outcome with at least 1 year follow-up.
These 34 patients were recognized as 14 familial cases (identical seizures affecting parents) and 11 non familial cases. The other nine cases had different or undefined epilepsy in the family. The clinical and EEG characteristics were the same: at the mean age of 6 months, brief partial seizures (often secondarily or apparently generalized) occurring in a cluster of two to 12 episodes a day for a mean duration of 2.5 days, with ictal EEG showing focal discharge, often slow waves or focal spikes on post-ictal tracing and normal interictal EEG.
The clinical and EEG characteristics are important in order to recognize this type of infantile convulsions (familial or not familial), which have a good prognosis and need no aggressive treatment.
良性婴儿非热性惊厥并不广为人知，这促使我们对其临床和脑电图特征进行研究。
在1981年至1994年间，我们纳入了34例符合以下标准的患者：年龄在1个月至2岁之间的非热性惊厥、个人史正常、临床、生物学和放射学检查无异常、至少随访1年发育结果正常。
这34例患者中，14例为家族性病例（父母有相同发作），11例为非家族性病例。另外9例患者家族中有不同或未明确的癫痫。其临床和脑电图特征相同：平均年龄6个月，短暂部分性发作（常继发或明显全身性发作），每天发作2至12次成簇出现，平均持续2.5天，发作期脑电图显示局灶性放电，发作后描记图常为慢波或局灶性棘波，发作间期脑电图正常。
临床和脑电图特征对于识别这类婴儿惊厥（家族性或非家族性）很重要，其预后良好，无需积极治疗。
