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足月引产时前列腺素与缩宫素的比较(作者译)

[Prostaglandins compared with oxytocin for induction of labour at term (author's transl)].

作者信息

Seidl A, Stopfer H, Gruber W, Fröhlich H, Baumgarten K

出版信息

Wien Klin Wochenschr. 1976 May 14;88(10):315-8.

PMID:997522
Abstract

12 cases of induction of labour with prostaglandin F2 alpha and 8 with prostaglandin E2 were compared with 14 cases in which induction was undertaken with oxytocin. All inductions were successful, the induction--delivery intervals being slightly shorter in the prostaglandin groups than in the oxytocin group. Both with prostaglandin F2 alpha and with prostaglandin E2 the cardiotocogram showed uterine hyperactivity in most of the cases with an unexpected, episodically-occurring increase in basal uterine tone and remarkable tachysystoly. Uterine hyper-activity led to fetal heart rate alterations of the "dip 2" type in about 50% of the cases. According to these results prostaglandins cannot be considered superior to oxytocin for the induction of labour at term.

摘要

将12例使用前列腺素F2α引产的病例和8例使用前列腺素E2引产的病例与14例使用缩宫素引产的病例进行了比较。所有引产均获成功,前列腺素组的引产至分娩间隔略短于缩宫素组。使用前列腺素F2α和前列腺素E2时,大多数病例的胎心监护图显示子宫活动过度,基础子宫张力意外地间歇性增加,伴有明显的子宫收缩过速。约50%的病例中,子宫活动过度导致了“凹陷2”型胎儿心率改变。根据这些结果,足月引产时,前列腺素并不优于缩宫素。

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