大剂量静脉注射苯唑西林治疗期间的中性粒细胞减少症。
Neutropenia during high dose intravenous oxacillin therapy.
作者信息
Ahern M J, Hicks J E, Andriole V T
出版信息
Yale J Biol Med. 1976 Sep;49(4):351-60.
Abstract
Five patients who developed neutropenia following intravenous administration of high dose oxacillin for serious Staphylococcus aureus infection are described. Neutropenia was reversible with cessation of intravenous oxacillin therapy. Two patients were continued on oral oxacillin without untoward effects.
摘要
本文描述了5例因静脉注射大剂量苯唑西林治疗严重金黄色葡萄球菌感染而发生中性粒细胞减少症的患者。停用静脉注射苯唑西林治疗后，中性粒细胞减少症可逆转。2例患者继续口服苯唑西林，未出现不良反应。
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引用本文的文献
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Unusually high occurrence of drug reactions with nafcillin.使用萘夫西林时药物不良反应的发生率异常高。
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本文引用的文献
1
The newer penicillins. II. Clinical experiences with methicillin and oxacillin.
Ann Intern Med. 1962 Sep;57:344-62. doi: 10.7326/0003-4819-57-3-344.
2
Neutropenia probably resulting from nafcillin.中性粒细胞减少症可能由萘夫西林引起。
JAMA. 1975 Jun 16;232(11):1152-4.
3
Nafcillin-induced agranulocytosis.
JAMA. 1975 Jun 16;232(11):1150-2.
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