Sedlarik K, Eger H, Wilde J, Vollmar F, Reimann G, Schilling B, Seelig G, Fiehring H
Z Exp Chir. 1976 Oct;9(5):302-15.
Coronary thrombosis was induced in 14 miniature pigs by means of direct current. The induction electrode was introduced via the common carotid artery into the coronary artery. The intensity of current (1 mA) and the duration of current flow (60 min) were kept constant in all the experimental animals. 6 miniature pigs survived the period of observation (48 h). In all instances, an injury to the intima was the morphopathological location factor. With the exception of one animal, which died after an induction time of 60 min, coronary thrombosis was stated in all the miniature pigs. The experimental arrangement which produces closed-thorax coronary thrombosis is suited for cardiosurgical, physiopathological and pharmacological experiments, especially because the anatomy and the degree of development of the porcine heart are most similar to those of the human heart.
通过直流电在14只小型猪中诱发冠状动脉血栓形成。将诱导电极经颈总动脉插入冠状动脉。所有实验动物的电流强度（1毫安）和电流持续时间（60分钟）保持恒定。6只小型猪存活至观察期结束（48小时）。在所有情况下，内膜损伤都是形态病理学定位因素。除一只在诱导60分钟后死亡的动物外，所有小型猪均出现冠状动脉血栓形成。这种产生闭胸冠状动脉血栓形成的实验装置适用于心脏外科、生理病理学和药理学实验，特别是因为猪心脏的解剖结构和发育程度与人类心脏最为相似。
