Hasslacher C, Wahl P, Thorspecken R, Nüssel E
Z Kardiol. 1976 Oct;65(10):890-6.
The frequency and distribution of risk factors of arteriosclerosis were determined in 405 patients with implanted cardiac pacemakers and compared with the corresponding results of patients with cardiac infarction. The most frequent risk factors were smoking (43,5%), hypertension (35,2%), and diabetes (34,3%) in males, hypertension (52,3%) and diabetes (49,7%) in females. The frequency of cardiac infarction was in average 19,5%. In the infarction group diabetes was lower in both sexes (23,5% and 35,8%), respectively), hyperlipoproteinemia and smoking were more frequent. From the different distribution of risk factors it is suggested, that coronary arteriosclerosis is not the most important etiologic factor in the development of bradycardic dysrhythmias. The higher percentage of diabetes in the pacemaker group could point to metabolic disturbances or specific diabetic vascular disease as harmful factors to the conduction system.
对405例植入心脏起搏器的患者进行了动脉硬化危险因素的频率和分布测定,并与心肌梗死患者的相应结果进行了比较。男性中最常见的危险因素是吸烟(43.5%)、高血压(35.2%)和糖尿病(34.3%),女性中是高血压(52.3%)和糖尿病(49.7%)。心肌梗死的发生率平均为19.5%。在梗死组中,两性的糖尿病发生率均较低(分别为23.5%和35.8%),高脂蛋白血症和吸烟更为常见。从危险因素的不同分布情况来看,提示冠状动脉硬化不是缓慢性心律失常发生的最重要病因。起搏器组中糖尿病比例较高可能表明代谢紊乱或特定的糖尿病血管病变是对传导系统有害的因素。