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[乳腺癌术前放疗及保乳根治性放疗(作者译)]

[Preoperative radiotherapy and curative radiotherapy without mastectomy in carcinoma of the breast (author's transl)].

作者信息

Sauer R

出版信息

Rontgenblatter. 1978 Jul;31(7):417-22.

PMID:99799
Abstract

The aim of preoperative radiotherapy of mastocarcinoma is to reduce the size of the tumor to enable radical surgery in the third stage. This method is preferable to postoperative radiotherapy for anatomical and radiobiological reasons. It has not yet been possible to prove beyond doubt that preoperative radiotherapy also has a favourable effect on symptom-free survival. Curative radiotherapy without mastectomy is recommended for tumors of 2 - 3 cm size which are mobile, in small and medium-sized breasts, if the axilla is free or has only 1 - 2 mobile lymphatic nodes. Tumorectomy must be followed by surgical revision of the axillary region. High-voltage equipment is mandotory for radiotherapy. Results obtained to date are in no way inferior to those of mastectomy. Local control rate is 90-100%. The cosmetic result is usually excellent.

摘要

乳腺癌术前放疗的目的是缩小肿瘤大小,以便在第三阶段进行根治性手术。出于解剖学和放射生物学原因,这种方法优于术后放疗。目前尚无法确凿证明术前放疗对无病生存期也有积极影响。对于大小为2 - 3厘米、可活动、位于中小乳房且腋窝无转移或仅有1 - 2个可活动淋巴结的肿瘤,建议进行不切除乳房的根治性放疗。肿瘤切除术后必须对腋窝区域进行手术修正。放疗必须使用高压设备。迄今为止所获得的结果绝不亚于乳房切除术。局部控制率为90 - 100%。美容效果通常极佳。

相似文献

1
[Preoperative radiotherapy and curative radiotherapy without mastectomy in carcinoma of the breast (author's transl)].[乳腺癌术前放疗及保乳根治性放疗(作者译)]
Rontgenblatter. 1978 Jul;31(7):417-22.
2
[Locally advanced non inflammatory breast cancer treated by combined chemotherapy and preoperative irradiation: updated results in a series of 120 patients].[局部晚期非炎性乳腺癌的联合化疗及术前放疗治疗:120例患者的最新结果]
Cancer Radiother. 2004 Jun;8(3):155-67. doi: 10.1016/j.canrad.2004.01.001.
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[Primary radiation therapy of breast cancer (author's transl)].乳腺癌的原发性放射治疗(作者译)
Strahlentherapie. 1981 Feb;157(2):71-80.
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Combined chemotherapy and preoperative irradiation for locally advanced noninflammatory breast cancer: updated results in a series of 120 patients.局部晚期非炎性乳腺癌的联合化疗与术前放疗:120例患者的最新结果
Int J Radiat Oncol Biol Phys. 2004 Jul 15;59(4):1062-73. doi: 10.1016/j.ijrobp.2003.12.034.
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Breast carcinoma and surgical treatment. Results from randomized studies.
Acta Chir Scand Suppl. 1984;519:19-24.
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[Contribution of radiotherapy in the local-regional treatment of breast cancer].[放射治疗在乳腺癌局部区域治疗中的贡献]
Schweiz Med Wochenschr. 1977 Jul 16;107(28):997-1002.
7
The incidence of lung carcinoma after surgery for breast carcinoma with and without postoperative radiotherapy. Results of National Surgical Adjuvant Breast and Bowel Project (NSABP) clinical trials B-04 and B-06.接受和未接受术后放疗的乳腺癌手术后肺癌的发病率。国家外科辅助乳腺和肠道项目(NSABP)临床试验B - 04和B - 06的结果。
Cancer. 2003 Oct 1;98(7):1362-8. doi: 10.1002/cncr.11655.
8
[Single preoperative radiation exposure for stage II breast cancer].[II期乳腺癌的术前单次放射暴露]
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A positive margin is not always an indication for radiotherapy after mastectomy in early breast cancer.切缘阳性并不总是早期乳腺癌乳房切除术后放疗的指征。
Int J Radiat Oncol Biol Phys. 2004 Mar 1;58(3):797-804. doi: 10.1016/S0360-3016(03)01626-2.
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[Bilateral radical mastectomy for carcinoma of the breast of the stages T0 and T1 (N0, M0) and mammoplasty of both breasts, areola and nipples in a single operation (author's transl)].
Geburtshilfe Frauenheilkd. 1976 Jan;36(1):10-9.