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延髓网状结构在决明种子提取物降压作用中的参与情况。

The involvement of medullary reticular formation in the hypotensive effect of extracts from seeds of Cassia tora.

作者信息

Chan S H, Koo A, Li K M

出版信息

Am J Chin Med (Gard City N Y). 1976;4(4):383-89. doi: 10.1142/s0192415x76000482.

DOI:10.1142/s0192415x76000482
PMID:998558
Abstract

In pentobarbital anesthetized rats, the medial portion of the medullary reticular formation has been identified to be directly involved in the hypotensive effect of extracts from the seeds of Cassia tora. This conclusion was drawn from the observed decrease in arterial blood pressure following local injection of extracts of this herb into this reticular site and from its inability to promote hypotension when the same reticular site has been electrolytically lesioned. The role of the medullary reticular formation in the Cassia tora-induced hypotension was suggested to be one which modulates the basic cardiovascular reflexes, favoring a decrease in vasomotor tone.

摘要

在戊巴比妥麻醉的大鼠中,已确定延髓网状结构的内侧部分直接参与决明子种子提取物的降压作用。这一结论是基于以下观察结果得出的:将这种草药的提取物局部注射到该网状部位后,动脉血压下降;而当相同的网状部位经电解损伤后,提取物无法促进血压降低。延髓网状结构在决明子诱导的低血压中的作用被认为是调节基本的心血管反射,有利于血管运动张力的降低。

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