Koo A, Chan W S, Li K M
Am J Chin Med (Gard City N Y). 1976 Autumn;4(3):249-55. doi: 10.1142/s0192415x76000342.
The Chinese medicinal herb Chueh-ming-tzu, seeds of Cassia tora (Leguminosae) Linn., elicits hypotensive effects in anesthetized rats. Experimental results indicate that the hypotensive effect of the Cassia tora extract possibly involves a vagal reflex which reciprocally alters the vasomotor tone of the centrally emanating sympathetic nervous system. It is shown that the capacity of the Cassia tora extract to reduce blood pressure is significantly reduced in vagotomized rats and that hypotensive effects are greatly antagonized in rats whose sympathetic nervous systems are interrupted by transection of the spinal cord.
中药决明子,即豆科植物决明(Cassia tora (Leguminosae) Linn.)的种子,对麻醉大鼠有降压作用。实验结果表明,决明提取物的降压作用可能涉及迷走神经反射,该反射可反向改变中枢发出的交感神经系统的血管运动张力。结果显示,在切断迷走神经的大鼠中,决明提取物降低血压的能力显著降低,并且在交感神经系统因脊髓横断而中断的大鼠中,降压作用受到极大拮抗。