Fixler D E, Atkins J M, Mitchell J H, Horwitz L D
Am J Physiol. 1976 Nov;231(5 Pt. 1):1515-9. doi: 10.1152/ajplegacy.1976.231.5.1515.
The distribution of cardiac output was analyzed in six dogs, with the animals at rest and running on a level treadmill for 3 min at 3-4 mph (mild exercise) and 3 min at 6-8 mph (moderate exercise). Organ flows were measured using 25-mug-diam radioactive microspheres. Cardiac output averaged 2.5, 4.6, and 5.7 liters/min, for rest, mild exercise, and moderate exercise, respectively. The greatest change was in diaphragmatic flow which increased by 275% with mild exercise and 500% with moderate exercise. Flow to intercostal muscles increased by 160 and 186%, to the exercising gastrocnemius muscle by 153 and 224%, and to cardiac muscle by 57 and 109% during mild and moderate exercise, respectively. Renal and cerebral flows did not change significantly. Significant decreases in flow occurred in the small and large intestines during moderate exercise. It is concluded that the increase in cardiac output during submaximal exercise was redistributed in a manner which limited flow to the brain, intestines, and kidneys and increased flow flow to the diaphragm, heart, and limb muscles.
对六只狗的心输出量分布进行了分析，这些动物处于静息状态，然后在水平跑步机上以3-4英里/小时的速度跑步3分钟（轻度运动），接着以6-8英里/小时的速度跑步3分钟（中度运动）。使用直径25微克的放射性微球测量器官血流量。静息、轻度运动和中度运动时的心输出量平均分别为2.5、4.6和5.7升/分钟。变化最大的是膈肌血流量，轻度运动时增加了275%，中度运动时增加了500%。轻度和中度运动期间，肋间肌血流量分别增加了160%和186%，运动中的腓肠肌血流量分别增加了153%和224%，心肌血流量分别增加了57%和109%。肾和脑血流量没有显著变化。中度运动期间，小肠和大肠的血流量显著减少。得出的结论是，次最大运动期间心输出量的增加以一种限制流向脑、肠和肾的血流量并增加流向膈肌、心脏和肢体肌肉的血流量的方式进行了重新分配。
