Jadusingh I H
Medical Laboratory Consultants, Calgary General Hospital, Alberta, Canada.
Acta Cytol. 1997 Jul-Aug;41(4 Suppl):1391-3. doi: 10.1159/000333546.
Fibrous hamartoma of infancy (FHI) is an uncommon, benign lesion with a distinctive histologic appearance, usually occurring as a small, rapidly growing soft tissue swelling developing in the first two years of life. Apart from one publication, there appear to be few descriptions of the fine needle aspiration biopsy (FNAB) features of this lesion. Detailed information on the clinical and FNAB findings in a patient with FHI is presented.
An 8-month-old female had a firm mass on the posterior aspect of the arm. FNAB produced smears that displayed moderate cellularity, loosely lying and clustered fibroblastic-appearing cells, fatty tissue and collagenous material without evidence of significant nuclear atypia or mitoses.
In the appropriate clinical setting, if the pathologist performing the microscopic evaluation can be confident that all the tissues with features as described are exclusively from the nodule, it is likely that a confident diagnosis of FHI can be made.
婴儿纤维性错构瘤（FHI）是一种罕见的良性病变，具有独特的组织学表现，通常表现为在生命的头两年出现的小的、快速生长的软组织肿胀。除了一篇文献外，关于该病变细针穿刺活检（FNAB）特征的描述似乎很少。本文介绍了一例FHI患者的临床及FNAB检查结果的详细信息。
一名8个月大的女性手臂后侧有一个质地坚硬的肿块。FNAB涂片显示细胞数量中等，有散在和聚集的成纤维细胞样细胞、脂肪组织和胶原物质，未见明显核异型性或核分裂象。
在适当的临床情况下，如果进行显微镜评估的病理学家能够确信所有具有所述特征的组织均仅来自结节，则很可能做出FHI的明确诊断。
