Shankar K R, Losty P D, Khine M M, Lamont G L, McDowell H P
Department of Paediatric Surgery, Alder Hey Children's Hospital, UK.
J R Coll Surg Edinb. 1998 Dec;43(6):422-3.
Pancreatic tumours are rare childhood neoplasms. Inflammatory myofibrohistiocytic tumours (IMTs) represent an uncommon but distinct pathological subgroup that creates diagnostic and therapeutic dilemmas. We report a case of IMT arising from the body and tail of the pancreas in an 8-year-old girl presenting with a mass and abdominal pain. A locally aggressive tumour with no evidence of distant metastasis was encountered at laparotomy and resected. Pathologically, the tumour revealed a mixed inflammatory cell infiltrate with myofibrohistiocytic proliferation. These features can resemble a sarcoma. A review of the literature is provided which emphasises the clinical features, pathological findings, and management strategies for these unusual tumours. Complete surgical excision, aided by radiological surveillance, appears to offer the best guidelines for definitive management.
胰腺肿瘤是罕见的儿童肿瘤。炎性肌纤维组织细胞瘤（IMTs）是一种不常见但独特的病理亚组，会造成诊断和治疗上的难题。我们报告一例8岁女孩发生于胰体尾的IMT，表现为肿块和腹痛。剖腹探查时发现一个局部侵袭性肿瘤，无远处转移证据，遂行切除。病理检查显示肿瘤有混合性炎性细胞浸润及肌纤维组织细胞增生。这些特征可能类似肉瘤。本文提供了文献综述，强调了这些不寻常肿瘤的临床特征、病理表现及治疗策略。在放射学监测辅助下的完整手术切除似乎为确定性治疗提供了最佳指导方针。
